The Panel responsible for maintaining the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIVpublished an update to the section on immunizations on November 18, 2021. Highlights of the update include:

• The immunizations section has been updated to reflect the recommendation that all people with HIV should receive a COVID-19 vaccine regardless of their CD4 T lymphocyte count or HIV viral load.
• People with advanced or untreated HIV who received a 2-dose series with one of the mRNA COVID-19 vaccines should receive a third dose of that vaccine at least 28 days after the second dose.
• The zoster vaccine is now recommended for people with HIV age 18 years old and older in alignment with Advisory Committee on Immunization Practices (ACIP)

View the Immunizations section.

In addition, Appendix B: Panel Roster and Financial Disclosures was also updated.

For a complete list of updates, please see What's New in the Guidelines. To view or download the guidelines, go to the Adult and Adolescent Opportunistic Infection Guidelines section of ClinicalInfo.hiv.gov. The guideline tables and recommendations can also be downloaded as separate PDF files.

These guidelines are prepared by the Opportunistic Infections Working Group under the auspices of the NIH Office of AIDS Research Advisory Council (OARAC), an authorized Federal Advisory Committee to the U.S. Department of Health and Human Services. These guidelines are intended for clinicians, other health care providers, patients with HIV, and policy makers in the United States.